Preheat the oven to 350°F and lightly grease a 9×5 loaf pan with cooking spray
Into a large bowl add 1 1/2 pounds lean ground beef along with the chopped onion, season with salt ,ground black pepper and garlic powder to taste, mix this together
Add in the cubed bread, a 1/2 cup milk and 1 egg and mix this together
Add 2 tbls of yellow mustard and a 1/4 cup of ketchup, mix all this together to combine the ingredients.
Place the mixture into your prepared meatloaf pan and spread it evenly, press it lightly.
In a small bowl add 1 tbsp of yellow mustard, a 1/4 of ketchup, 3 tbsp of brown sugar, stir to combine. pour the mixture over the meatloaf and spread it evenly over the top
Bake the meatloaf in the preheated oven for 2 hours or untill the internal temperature, which is 165° is measured on a thermometer